SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04339

Signal sequence   MGKSSEAWCIVLFSVFASFSA

Length  21

Organism  Mesocricetus auratus (Golden hamster)

UniProt ID  P15156,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04339.cif

Structure  SPKB04339.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2267.64254

Aliphatic index  79.04761905

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  825.58

Aromaticity  0.19047619

Average rotatable bonds  3.380952381

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -6.7201

Hydropathy 



Literature Information


Title  Complete primary structure of calcium-dependent serine proteinase capable of degrading extracellular matrix proteins.

DOI  10.1016/0014-5793(89)80766-5,

Publication Year  1989

PubMed ID  2753140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.