SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04337

Signal sequence   MLGSKRLGLSGLTLALSLLVCLGALAEA

Length  28

Organism  Ovis aries (Sheep)

UniProt ID  P14765,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04337.cif

Structure  SPKB04337.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2771.41284

Aliphatic index  163.9285714

Isoelectric point  8.545125282

Charge (pH=7)   0.937486361

Topological polar surface area  1055.16

Aromaticity  0

Average rotatable bonds  3.392857143

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -8.49223

Hydropathy 



Literature Information


Title  Sheep neuropeptide Y. A third structural type of a highly conserved peptide.

DOI  10.1016/0014-5793(89)81669-2,

Publication Year  1989

PubMed ID  2599092,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.