SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04336

Signal sequence   MFLIYLFVQTAES

Length  13

Organism  Ascaris suum (Pig roundworm) (Ascaris lumbricoides)

UniProt ID  P14661,

Motif  1..13



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04336.cif

Structure  SPKB04336.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1561.85614

Aliphatic index  120

Isoelectric point  3.849982713

Charge (pH=7)   -1.001090992

Topological polar surface area  553.6

Aromaticity  0.230769231

Average rotatable bonds  3.769230769

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  -1.2797

Hydropathy 



Literature Information


Title  Ascaris nematodes from pig and human make three antibacterial peptides: isolation of cecropin P1 and two ASABF peptides.

DOI  10.1007/s000180300051,

Publication Year  2003

PubMed ID  12737319,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.