SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04335

Signal sequence   MKKLVIALCLMMVLAVMVEEAEA

Length  23

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  P14213,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04335.cif

Structure  SPKB04335.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2536.26174

Aliphatic index  152.6086957

Isoelectric point  4.479375319

Charge (pH=7)   -1.059255116

Topological polar surface area  867.46

Aromaticity  0

Average rotatable bonds  3.869565217

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  34

X logP energy  -1.2074

Hydropathy 



Literature Information


Title  Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure.

DOI  NA,

Publication Year  1988

PubMed ID  3141410,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.