SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04323

Signal sequence   MDPQTALSRALLLLLFLHLSLLGCRS

Length  26

Organism  Bos taurus (Bovine)

UniProt ID  P13204,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04323.cif

Structure  SPKB04323.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2882.51854

Aliphatic index  157.6923077

Isoelectric point  8.55739952

Charge (pH=7)   1.027358536

Topological polar surface area  1095.82

Aromaticity  0.038461538

Average rotatable bonds  3.653846154

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  38

X logP energy  -7.32746

Hydropathy 



Literature Information


Title  Purification and primary structure of pro-aldosterone secretion inhibitory factor from bovine adrenal chromaffin cells.

DOI  10.1210/mend-3-11-1823,

Publication Year  1989

PubMed ID  2532709,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.