SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04317

Signal sequence   MALSITRGLLLLAALCCLAPTSLA

Length  24

Organism  Ovis aries (Sheep)

UniProt ID  P12725,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04317.cif

Structure  SPKB04317.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2416.03674

Aliphatic index  167.0833333

Isoelectric point  8.231408964

Charge (pH=7)   0.874031556

Topological polar surface area  866.65

Aromaticity  0

Average rotatable bonds  3.208333333

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -6.17713

Hydropathy 



Literature Information


Title  Isolation and characterization of sheep alpha 1-proteinase inhibitor.

DOI  10.1042/bj2730685,

Publication Year  1991

PubMed ID  1899999,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.