General Information
SPKB ID SPKB04316
Signal sequence MALWMQCLPLVLVLLFSTPNTEA
Length 23
Organism Xenopus laevis (African clawed frog)
UniProt ID P12707,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04316.cif
Physicochemical Information
Molecular weight 2591.18004
Aliphatic index 135.6521739
Isoelectric point 3.849962145
Charge (pH=7) -1.062215294
Topological polar surface area 885.9
Aromaticity 0.086956522
Average rotatable bonds 3.434782609
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 33
X logP energy -3.133
Hydropathy
Literature Information
Title Isolation and characterization of two different insulins from an amphibian, Xenopus laevis.
Publication Year 1989
PubMed ID 2661211,
Patent ID NA,