SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04314

Signal sequence   MDKKRSSLKGSLLLLLLLVSDLLLCKSVAS

Length  30

Organism  Equus caballus (Horse)

UniProt ID  P12420,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04314.cif

Structure  SPKB04314.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3245.02624

Aliphatic index  165.6666667

Isoelectric point  10.33750544

Charge (pH=7)   2.935719105

Topological polar surface area  1269.18

Aromaticity  0

Average rotatable bonds  3.9

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  46

X logP energy  -9.70673

Hydropathy 



Literature Information


Title  Primary structure of equine pituitary prolactin.

DOI  10.1111/j.1399-3011.1988.tb00913.x,

Publication Year  1988

PubMed ID  3045032,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.