SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04312

Signal sequence   MWLCALALASLAACTAWG

Length  18

Organism  Oryctolagus cuniculus (Rabbit)

UniProt ID  P12337,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04312.cif

Structure  SPKB04312.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1852.25744

Aliphatic index  120

Isoelectric point  5.826007312

Charge (pH=7)   -0.125965132

Topological polar surface area  630.06

Aromaticity  0.111111111

Average rotatable bonds  3

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -2.9911

Hydropathy 



Literature Information


Title  Complete covalent structure of 60-kDa esterase isolated from 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced rabbit liver microsomes.

DOI  NA,

Publication Year  1988

PubMed ID  3343253,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.