SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04304

Signal sequence   MMAGMKIQLVCMILLAFSSWSLC

Length  23

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P10673,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04304.cif

Structure  SPKB04304.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2577.29094

Aliphatic index  123.0434783

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  849.11

Aromaticity  0.086956522

Average rotatable bonds  3.739130435

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  35

X logP energy  -3.1222

Hydropathy 



Literature Information


Title  Purification of large neuromedin N (NMN) from canine intestine and its identification as NMN-125.

DOI  10.1016/0006-291x(91)91369-n,

Publication Year  1991

PubMed ID  1883359,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.