SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04291

Signal sequence   MRHLLVLLLICLSVIAMAQA

Length  20

Organism  Doratifera vulnerans (Mottled cup moth)

UniProt ID  P0DUT6,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04291.cif

Structure  SPKB04291.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2208.85354

Aliphatic index  200

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  770.12

Aromaticity  0

Average rotatable bonds  3.7

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -1.72713

Hydropathy 



Literature Information


Title  Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans.

DOI  10.1073/pnas.2023815118,

Publication Year  2021

PubMed ID  33893140,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.