SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04288

Signal sequence   MRLILLSGLLLLGTFLANG

Length  19

Organism  Cerrophidion godmani (Porthidium godmani) (Bothrops godmani)

UniProt ID  P0DQP8,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04288.cif

Structure  SPKB04288.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2015.52814

Aliphatic index  190

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  732.57

Aromaticity  0.052631579

Average rotatable bonds  3.578947368

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  25

X logP energy  -3.03873

Hydropathy 



Literature Information


Title  Two phospholipase A2 inhibitors from the plasma of Cerrophidion (Bothrops) godmani which selectively inhibit two different group-II phospholipase A2 myotoxins from its own venom: isolation, molecular cloning and biological properties.

DOI  NA,

Publication Year  2000

PubMed ID  10698689,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.