SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04287

Signal sequence   MKYLHTICLLFIFVARGNS

Length  19

Organism  Cerrophidion godmani (Porthidium godmani) (Bothrops godmani)

UniProt ID  P0DQP7,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04287.cif

Structure  SPKB04287.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2226.72594

Aliphatic index  123.1578947

Isoelectric point  9.449118783

Charge (pH=7)   2.025769915

Topological polar surface area  807.5

Aromaticity  0.157894737

Average rotatable bonds  3.789473684

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -3.61433

Hydropathy 



Literature Information


Title  Two phospholipase A2 inhibitors from the plasma of Cerrophidion (Bothrops) godmani which selectively inhibit two different group-II phospholipase A2 myotoxins from its own venom: isolation, molecular cloning and biological properties.

DOI  NA,

Publication Year  2000

PubMed ID  10698689,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.