SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04286

Signal sequence   MKGMILFISCILLIGIVVEC

Length  20

Organism  Tityus trivittatus (Argentinean scorpion)

UniProt ID  P0DMM8,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04286.cif

Structure  SPKB04286.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2195.86664

Aliphatic index  185

Isoelectric point  6.13535235

Charge (pH=7)   -0.124485044

Topological polar surface area  699.77

Aromaticity  0.05

Average rotatable bonds  3.75

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  0.1477

Hydropathy 



Literature Information


Title  Biochemical and physiological characterization of a new Na(+)-channel specific peptide from the venom of the Argentinean scorpion Tityus trivittatus.

DOI  10.1016/j.peptides.2014.05.002,

Publication Year  2015

PubMed ID  24862827,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.