SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04284

Signal sequence   MNKVKFYVLFTALLSSLCAHG

Length  21

Organism  Escherichia coli

UniProt ID  P0CK94,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04284.cif

Structure  SPKB04284.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2342.84274

Aliphatic index  111.4285714

Isoelectric point  9.407025159

Charge (pH=7)   2.025478192

Topological polar surface area  850.05

Aromaticity  0.142857143

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -5.1569

Hydropathy 



Literature Information


Title  A unique amino acid sequence of the B subunit of a heat-labile enterotoxin isolated from a human enterotoxigenic Escherichia coli.

DOI  10.1016/0882-4010(87)90079-9,

Publication Year  1987

PubMed ID  3333803,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.