SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04283

Signal sequence   MSRLYAIILIALVLNVIMTIMPDSKVEA

Length  28

Organism  Odontobuthus doriae (Yellow Iranian scorpion)

UniProt ID  P0CC12,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04283.cif

Structure  SPKB04283.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3118.88554

Aliphatic index  167.1428571

Isoelectric point  6.487519403

Charge (pH=7)   -0.000942853

Topological polar surface area  1126.76

Aromaticity  0.035714286

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  41

X logP energy  -4.38313

Hydropathy 



Literature Information


Title  The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae.

DOI  10.1016/j.febslet.2006.10.029,

Publication Year  2006

PubMed ID  17070524,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.