General Information
SPKB ID SPKB04282
Signal sequence MKVFFAVLIALFVCSMVIGIHG
Length 22
Organism Buthus israelis (Israeli scorpion) (Buthus occitanus israelis)
UniProt ID P0C908,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04282.cif
Physicochemical Information
Molecular weight 2396.05124
Aliphatic index 150.4545455
Isoelectric point 8.552755748
Charge (pH=7) 1.026623641
Topological polar surface area 749.35
Aromaticity 0.136363636
Average rotatable bonds 3.5
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 29
X logP energy -0.0126
Hydropathy
Literature Information
Title Isolation of the first toxin from the scorpion Buthus occitanus israelis showing preference for Shaker potassium channels.
DOI 10.1016/j.febslet.2007.04.065,
Publication Year 2007
PubMed ID 17490656,
Patent ID NA,