General Information
SPKB ID SPKB04281
Signal sequence MRALLARLLLCVLVVSDSKG
Length 20
Organism Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
UniProt ID P0C8E8,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04281.cif
Physicochemical Information
Molecular weight 2157.70444
Aliphatic index 170.5
Isoelectric point 9.828249571
Charge (pH=7) 1.936154411
Topological polar surface area 843.8
Aromaticity 0
Average rotatable bonds 3.7
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 29
X logP energy -5.67696
Hydropathy
Literature Information
Title Ticks produce highly selective chemokine binding proteins with antiinflammatory activity.
DOI 10.1084/jem.20072689,
Publication Year 2008
PubMed ID 18678732,
Patent ID NA,