SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04280

Signal sequence   MNFRRMLCAAIVLTIVLSIMLPSTVFA

Length  27

Organism  Acetivibrio thermocellus (Hungateiclostridium thermocellum) (Clostridium thermocellum)

UniProt ID  P0C2S1,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04280.cif

Structure  SPKB04280.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3011.79714

Aliphatic index  144.4444444

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1058.94

Aromaticity  0.074074074

Average rotatable bonds  3.592592593

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  39

X logP energy  -5.31766

Hydropathy 



Literature Information


Title  Dissociation of the cellulosome of Clostridium thermocellum in the presence of ethylenediaminetetraacetic acid occurs with the formation of trucated polypeptides.

DOI  10.1021/bi9524629,

Publication Year  1996

PubMed ID  8664281,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.