SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04279

Signal sequence   MNSKLTALIFLGLVAIASC

Length  19

Organism  Heterometrus laoticus (Thai giant scorpion)

UniProt ID  P0C2F4,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04279.cif

Structure  SPKB04279.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1965.43994

Aliphatic index  154.2105263

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  716.92

Aromaticity  0.052631579

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.9562

Hydropathy 



Literature Information


Title  Purification and characterization of Heteroscorpine-1 (HS-1) toxin from Heterometrus laoticus scorpion venom.

DOI  10.1016/j.toxicon.2006.09.003,

Publication Year  2007

PubMed ID  17056081,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.