SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04277

Signal sequence   MKGMIMLISCLMLIDVVVES

Length  20

Organism  Tityus discrepans (Venezuelan scorpion)

UniProt ID  P0C1X7,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04277.cif

Structure  SPKB04277.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2225.86514

Aliphatic index  160.5

Isoelectric point  4.184374539

Charge (pH=7)   -1.062063843

Topological polar surface area  757.3

Aromaticity  0

Average rotatable bonds  3.9

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  31

X logP energy  -2.1192

Hydropathy 



Literature Information


Title  Ardiscretin a novel arthropod-selective toxin from Tityus discrepans scorpion venom.

DOI  10.1016/j.toxicon.2003.12.004,

Publication Year  2004

PubMed ID  15033324,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.