Peptide-Information

General Information

SPKB ID SPKB04276

Signal sequence MEGRRFAAVLILTICMLAPGTGTLLP

Length 26

Organism Conus striatus (Striated cone)

UniProt ID P0C1X2,

Motif 1..26

Activity Information

Pathway SRP-dependent

Natural/Artificial Natural

Subcellular location ER

Secretion efficiency NA

Type Sec/SPI

Structure Information

PDB ID NA,

Predicted Structure ID SPKB04276.cif

Structure SPKB04276.cif

Very high (pLDDT > 90)

Confident (90 > pLDDT > 70)

Low (70 > pLDDT > 50)

Very low (pLDDT < 50)

Loading PAE…

Expected Position Error (Ångströms)

Physicochemical Information

Molecular weight 2745.39554

Aliphatic index 127.6923077

Isoelectric point 8.549845238

Charge (pH=7) 0.937778084

Topological polar surface area 995.03

Aromaticity 0.038461538

Average rotatable bonds 3.346153846

Number of hydrogen bond donors 36

Number of hydrogen bond acceptors 36

X logP energy -6.32426

Hydropathy

Literature Information

Title Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization.

Publication Year 2005

PubMed ID 15833744,

Patent ID NA,