SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04274

Signal sequence   MKVAYLLVLFTIMMLANDASL

Length  21

Organism  Opisthacanthus madagascariensis (Scorpion)

UniProt ID  P0C194,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04274.cif

Structure  SPKB04274.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2357.95344

Aliphatic index  153.3333333

Isoelectric point  6.330585692

Charge (pH=7)   -0.002714665

Topological polar surface area  812.42

Aromaticity  0.095238095

Average rotatable bonds  3.714285714

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  31

X logP energy  -1.9549

Hydropathy 



Literature Information


Title  Solution structure of IsTX. A male scorpion toxin from Opisthacanthus madagascariensis (Ischnuridae).

DOI  10.1111/j.1432-1033.2004.04322.x,

Publication Year  2004

PubMed ID  15373831,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.