SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04272

Signal sequence   MNKWGVGLTFLLAATSVMA

Length  19

Organism  Escherichia coli (strain K12)

UniProt ID  P0AG78,

Motif  1..19



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04272.cif

Structure  SPKB04272.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2010.44014

Aliphatic index  107.8947368

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  732.71

Aromaticity  0.105263158

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -4.8713

Hydropathy 



Literature Information


Title  Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli.

DOI  10.1111/j.1432-1033.1996.0773u.x,

Publication Year  1996

PubMed ID  8774726,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.