SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04271

Signal sequence   MKKWSRHLLAAGALALGMSAAHA

Length  23

Organism  Escherichia coli (strain K12)

UniProt ID  P0AFK9,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8Y5H,

Predicted Structure ID  SPKB04271.cif

Structure  SPKB04271.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2391.88094

Aliphatic index  98.26086957

Isoelectric point  11.82306892

Charge (pH=7)   3.179209102

Topological polar surface area  931.07

Aromaticity  0.043478261

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  33

X logP energy  -7.68193

Hydropathy 



Literature Information


Title  Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.

DOI  NA,

Publication Year  1991

PubMed ID  1939142,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.