SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04268

Signal sequence   MNIKGKALLAGCIALAFSNMALA

Length  23

Organism  Escherichia coli (strain K12)

UniProt ID  P0AD96,

Motif  1..23



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04268.cif

Structure  SPKB04268.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2321.88284

Aliphatic index  127.826087

Isoelectric point  9.676237541

Charge (pH=7)   1.935419516

Topological polar surface area  861.97

Aromaticity  0.043478261

Average rotatable bonds  3.434782609

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  32

X logP energy  -6.5975

Hydropathy 



Literature Information


Title  The primary structure of a Leu, Ile and Val (LIV)-binding protein from Escherichia coli.

DOI  10.1016/0014-5793(77)80331-1,

Publication Year  1977

PubMed ID  328304,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.