SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04260

Signal sequence   MLAFLILVTVTLASA

Length  15

Organism  Sus scrofa (Pig)

UniProt ID  P09955,

Motif  1..15



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04260.cif

Structure  SPKB04260.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1562.97144

Aliphatic index  188.6666667

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  531.41

Aromaticity  0.066666667

Average rotatable bonds  3.266666667

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  20

X logP energy  -1.4626

Hydropathy 



Literature Information


Title  Analysis of the activation process of porcine procarboxypeptidase B and determination of the sequence of its activation segment.

DOI  10.1021/bi00230a038,

Publication Year  1991

PubMed ID  2018774,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.