SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04253

Signal sequence   MKKSILALSLLVGLSTAASSYA

Length  22

Organism  Escherichia coli (strain K12)

UniProt ID  P09551,

Motif  1..22



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04253.cif

Structure  SPKB04253.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2224.68424

Aliphatic index  137.7272727

Isoelectric point  10.24760792

Charge (pH=7)   1.996543817

Topological polar surface area  868.07

Aromaticity  0.045454545

Average rotatable bonds  3.409090909

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -8.4756

Hydropathy 



Literature Information


Title  Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

DOI  10.1002/elps.1150180807,

Publication Year  1997

PubMed ID  9298646,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.