SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04244

Signal sequence   MPRKWISALFLLQISYCFKSGHC

Length  23

Organism  Rattus norvegicus (Rat)

UniProt ID  P08541,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04244.cif

Structure  SPKB04244.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2729.31434

Aliphatic index  89.13043478

Isoelectric point  9.497838541

Charge (pH=7)   2.963500165

Topological polar surface area  977.15

Aromaticity  0.173913043

Average rotatable bonds  3.782608696

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -5.04823

Hydropathy 



Literature Information


Title  Acyl-CoA binding and acylation of UDP-glucuronosyltransferase isoforms of rat liver: their effect on enzyme activity.

DOI  10.1042/bj3120301,

Publication Year  1995

PubMed ID  7492328,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.