SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04234

Signal sequence   MWLRCLALALTLLMVSG

Length  17

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  P06908,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04234.cif

Structure  SPKB04234.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1891.42174

Aliphatic index  166.4705882

Isoelectric point  8.549912035

Charge (pH=7)   0.936006272

Topological polar surface area  647.07

Aromaticity  0.058823529

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -1.44473

Hydropathy 



Literature Information


Title  Structure of canine pulmonary surfactant apoprotein: cDNA and complete amino acid sequence.

DOI  10.1073/pnas.82.19.6379,

Publication Year  1985

PubMed ID  3863100,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.