SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04233

Signal sequence   MLTFHRIIRKGWMFLLAFLLTALLFCPTGQPAKA

Length  34

Organism  Geobacillus stearothermophilus (Bacillus stearothermophilus)

UniProt ID  P06279,

Motif  1..34



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04233.cif

Structure  SPKB04233.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3906.85614

Aliphatic index  115

Isoelectric point  11.65160089

Charge (pH=7)   4.026321984

Topological polar surface area  1330.13

Aromaticity  0.147058824

Average rotatable bonds  3.647058824

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  47

X logP energy  -3.54456

Hydropathy 



Literature Information


Title  Efficient synthesis and secretion of a thermophilic alpha-amylase by protein-producing Bacillus brevis 47 carrying the Bacillus stearothermophilus amylase gene.

DOI  10.1128/jb.164.3.1182-1187.1985,

Publication Year  1985

PubMed ID  2999073,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.