SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04231

Signal sequence   MKTFHGPTFGTAVFLYLLLFLTSA

Length  24

Organism  Limulus polyphemus (Atlantic horseshoe crab)

UniProt ID  P06206,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04231.cif

Structure  SPKB04231.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2676.21174

Aliphatic index  101.6666667

Isoelectric point  9.300695891

Charge (pH=7)   1.087747942

Topological polar surface area  899.91

Aromaticity  0.208333333

Average rotatable bonds  3.375

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -3.4735

Hydropathy 



Literature Information


Title  The amino acid sequence of Limulus C-reactive protein. Evidence of polymorphism.

DOI  NA,

Publication Year  1986

PubMed ID  2426265,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.