SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04230

Signal sequence   MKTFHGPTCGTAVSLCLLLFLTSA

Length  24

Organism  Limulus polyphemus (Atlantic horseshoe crab)

UniProt ID  P06205,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04230.cif

Structure  SPKB04230.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2512.03834

Aliphatic index  101.6666667

Isoelectric point  8.241247528

Charge (pH=7)   0.964648925

Topological polar surface area  899.91

Aromaticity  0.083333333

Average rotatable bonds  3.25

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -8.0553

Hydropathy 



Literature Information


Title  The amino acid sequence of Limulus C-reactive protein. Evidence of polymorphism.

DOI  NA,

Publication Year  1986

PubMed ID  2426265,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.