SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04228

Signal sequence   MKLLTSLVFCSLLLGVCHG

Length  19

Organism  Mus musculus (Mouse)

UniProt ID  P05366,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04228.cif

Structure  SPKB04228.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2034.56414

Aliphatic index  153.6842105

Isoelectric point  8.241247528

Charge (pH=7)   0.964648925

Topological polar surface area  702.51

Aromaticity  0.052631579

Average rotatable bonds  3.526315789

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -3.7083

Hydropathy 



Literature Information


Title  Isolation and purification of two major serum amyloid A isotypes SAA1 and SAA2 from the acute phase plasma of mice.

DOI  10.1016/s0378-4347(97)00462-3,

Publication Year  1997

PubMed ID  9518179,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.