SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04226

Signal sequence   MDGIFCALPLSLLLLLQSCGVWG

Length  23

Organism  Gallus gallus (Chicken)

UniProt ID  P05099,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04226.cif

Structure  SPKB04226.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2450.00994

Aliphatic index  152.6086957

Isoelectric point  3.749955547

Charge (pH=7)   -1.125518648

Topological polar surface area  831.37

Aromaticity  0.086956522

Average rotatable bonds  3.347826087

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -3.1868

Hydropathy 



Literature Information


Title  Structure of the gene for cartilage matrix protein, a modular protein of the extracellular matrix. Exon/intron organization, unusual splice sites, and relation to alpha chains of beta 2 integrins, von Willebrand factor, complement factors B and C2, and epidermal growth factor.

DOI  NA,

Publication Year  1989

PubMed ID  2542265,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.