SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04221

Signal sequence   MEMFQGLLLWLLLGVAGVWA

Length  20

Organism  Bos taurus (Bovine)

UniProt ID  P04651,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6P57,

Predicted Structure ID  SPKB04221.cif

Structure  SPKB04221.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2247.78454

Aliphatic index  156

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  728.19

Aromaticity  0.15

Average rotatable bonds  3.55

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  1.4593

Hydropathy 



Literature Information


Title  Luteinizing hormone. The primary structures of the beta-subunit from bovine and porcine species.

DOI  10.1111/j.1432-1033.1973.tb03121.x,

Publication Year  1973

PubMed ID  4770795,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.