SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04218

Signal sequence   MIRYIILGLLTLASAHG

Length  17

Organism  Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

UniProt ID  P04494,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04218.cif

Structure  SPKB04218.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1842.27294

Aliphatic index  172.3529412

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  680.19

Aromaticity  0.058823529

Average rotatable bonds  3.529411765

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -2.91603

Hydropathy 



Literature Information


Title  The 19-kDa glycoprotein coded by region E3 of adenovirus. Purification, characterization, and structural analysis.

DOI  NA,

Publication Year  1985

PubMed ID  3882694,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.