General Information
SPKB ID SPKB04217
Signal sequence MDMRVLAQLLGLLLLCFPGARC
Length 22
Organism Homo sapiens (Human)
UniProt ID P04430,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04217.cif
Physicochemical Information
Molecular weight 2434.07544
Aliphatic index 146.3636364
Isoelectric point 8.231404231
Charge (pH=7) 0.874474729
Topological polar surface area 869.82
Aromaticity 0.045454545
Average rotatable bonds 3.636363636
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 31
X logP energy -3.75816
Hydropathy 
Literature Information
Title Polymorphism in a kappa I primary (AL) amyloid protein (BAN).
DOI 10.1016/0161-5890(86)90173-2,
Publication Year 1986
PubMed ID 3083240,
Patent ID NA,
