SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04193

Signal sequence   MEKKLFGIALLLTTVASVLA

Length  20

Organism  Tachypleus tridentatus (Japanese horseshoe crab)

UniProt ID  P02681,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04193.cif

Structure  SPKB04193.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2118.64644

Aliphatic index  161

Isoelectric point  9.537300927

Charge (pH=7)   0.999169354

Topological polar surface area  766.25

Aromaticity  0.05

Average rotatable bonds  3.6

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -3.2383

Hydropathy 



Literature Information


Title  Amino acid sequence studies on horseshoe crab (Tachypleus tridentatus) coagulogen and the mechanism of gel formation.

DOI  NA,

Publication Year  1979

PubMed ID  504251,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.