General Information
SPKB ID SPKB04190
Signal sequence MKHLWFFLLLVAAPRWVLS
Length 19
Organism Homo sapiens (Human)
UniProt ID P01825,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6J6Y,
Predicted Structure ID SPKB04190.cif
Physicochemical Information
Molecular weight 2327.90484
Aliphatic index 143.6842105
Isoelectric point 11.65178972
Charge (pH=7) 2.088595045
Topological polar surface area 746.74
Aromaticity 0.210526316
Average rotatable bonds 3.684210526
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 25
X logP energy 2.25007
Hydropathy 
Literature Information
Title Amino acid sequence of the VH region of a human myeloma immunoglobulin (IgG New).
DOI 10.1021/bi00634a019,
Publication Year 1977
PubMed ID 407927,
Patent ID NA,
