SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04189

Signal sequence   MDLMCKKMKHLWFFLLLVAAPRWVLS

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P01824,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6J6Y,

Predicted Structure ID  SPKB04189.cif

Structure  SPKB04189.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3178.02504

Aliphatic index  120

Isoelectric point  10.50678663

Charge (pH=7)   3.026476746

Topological polar surface area  1039.78

Aromaticity  0.153846154

Average rotatable bonds  3.961538462

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  38

X logP energy  0.85847

Hydropathy 



Literature Information


Title  Complete amino acid sequence of the delta heavy chain of human immunoglobulin D.

DOI  10.1073/pnas.79.9.2850,

Publication Year  1982

PubMed ID  6806818,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.