SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04188

Signal sequence   MELGLSWIFLLAILKGVQC

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01782,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04188.cif

Structure  SPKB04188.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2134.66594

Aliphatic index  164.2105263

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  729.55

Aromaticity  0.105263158

Average rotatable bonds  3.736842105

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -0.7127

Hydropathy 



Literature Information


Title  Amino acid sequence of the heavy-chain variable region of the crystallizable human myeloma protein Dob.

DOI  10.1021/bi00586a003,

Publication Year  1979

PubMed ID  114209,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.