General Information
SPKB ID SPKB04184
Signal sequence MDWTWRVFCLLAVAPGAHS
Length 19
Organism Homo sapiens (Human)
UniProt ID P01743,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 7A5R,
Predicted Structure ID SPKB04184.cif
Physicochemical Information
Molecular weight 2160.53914
Aliphatic index 87.36842105
Isoelectric point 7.359696704
Charge (pH=7) 0.027361847
Topological polar surface area 778.25
Aromaticity 0.157894737
Average rotatable bonds 3.263157895
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 27
X logP energy -3.82333
Hydropathy
Literature Information
Title Amino acid sequence of the variable region of heavy chain in immunoglobulin (Mot) having unusual papain cleavage sites.
DOI 10.1016/0161-5890(86)90039-8,
Publication Year 1986
PubMed ID 3084950,
Patent ID NA,