General Information
SPKB ID SPKB04182
Signal sequence MAWIPLLLPLLTLCTGSEA
Length 19
Organism Homo sapiens (Human)
UniProt ID P01717,
Motif 1..19
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04182.cif
Physicochemical Information
Molecular weight 2042.52244
Aliphatic index 154.2105263
Isoelectric point 3.849962145
Charge (pH=7) -1.062215294
Topological polar surface area 683.32
Aromaticity 0.052631579
Average rotatable bonds 3.210526316
Number of hydrogen bond donors 24
Number of hydrogen bond acceptors 26
X logP energy -1.8434
Hydropathy
Literature Information
Title Amino acid sequence of the variable region of the light (lambda) chain from human myeloma cryoimmunoglobulin IgG Hil.
DOI 10.1021/bi00602a021,
Publication Year 1978
PubMed ID 418804,
Patent ID NA,