General Information
SPKB ID SPKB04181
Signal sequence MAWIPLFLGVLAYCTGSVAS
Length 20
Organism Homo sapiens (Human)
UniProt ID P01715,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB04181.cif
Physicochemical Information
Molecular weight 2099.53364
Aliphatic index 122
Isoelectric point 5.919503212
Charge (pH=7) -0.064840831
Topological polar surface area 704.14
Aromaticity 0.15
Average rotatable bonds 3.05
Number of hydrogen bond donors 26
Number of hydrogen bond acceptors 27
X logP energy -3.1021
Hydropathy
Literature Information
Title Structural studies of a carbohydrate-containing immunoglobulin-lambda-light-chain amyloid-fibril protein (AL) of variable subgroup III.
DOI 10.1042/bj2390545,
Publication Year 1986
PubMed ID 3103603,
Patent ID NA,