SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04180

Signal sequence   MAWTPLWLTLLTLCIGSVVS

Length  20

Organism  Homo sapiens (Human)

UniProt ID  P01714,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04180.cif

Structure  SPKB04180.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2204.71374

Aliphatic index  151

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  740.16

Aromaticity  0.1

Average rotatable bonds  3.25

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  28

X logP energy  -2.3865

Hydropathy 



Literature Information


Title  The amino acid sequence of a lambda type Bence-Jones protein. 3. The complete amino acid sequence and the location of the disulfide bridges.

DOI  NA,

Publication Year  1970

PubMed ID  4909564,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.