SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04177

Signal sequence   MRLPAQLLGLLMLWVPGSS

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P01614,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04177.cif

Structure  SPKB04177.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2082.59324

Aliphatic index  143.6842105

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  730.78

Aromaticity  0.052631579

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.90403

Hydropathy 



Literature Information


Title  The complete amino acid sequence of Bence Jones protein Cum (kappa-type)

DOI  NA,

Publication Year  1967

PubMed ID  5586923,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.