SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04170

Signal sequence   MNSLLIITACLFLIGTVWA

Length  19

Organism  Centruroides sculpturatus (Arizona bark scorpion)

UniProt ID  P01493,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04170.cif

Structure  SPKB04170.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2079.58654

Aliphatic index  169.4736842

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  706.69

Aromaticity  0.105263158

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -1.9465

Hydropathy 



Literature Information


Title  Amino acid sequences of neurotoxic protein variants from the venom of Centruroides sculpturatus Ewing.

DOI  10.1016/0003-9861(74)90082-4,

Publication Year  1974

PubMed ID  4460885,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.