SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04169

Signal sequence   MNSLLMITACLVLIGTVWA

Length  19

Organism  Centruroides sculpturatus (Arizona bark scorpion)

UniProt ID  P01491,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04169.cif

Structure  SPKB04169.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2049.57574

Aliphatic index  164.2105263

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  706.69

Aromaticity  0.052631579

Average rotatable bonds  3.421052632

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -2.8262

Hydropathy 



Literature Information


Title  Amino acid sequence of neurotoxin I from Centruroides sculpturatus Ewing.

DOI  10.1016/0003-9861(75)90371-9,

Publication Year  1975

PubMed ID  1122130,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.