SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB04163

Signal sequence   MAVWIQAGALLFLLAVSSVNA

Length  21

Organism  Cyprinus carpio (Common carp)

UniProt ID  P01335,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB04163.cif

Structure  SPKB04163.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2174.62924

Aliphatic index  158.0952381

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  787.75

Aromaticity  0.095238095

Average rotatable bonds  3.238095238

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -4.131

Hydropathy 



Literature Information


Title  Carp insulin: amino acid sequence, biological activity and structural properties.

DOI  10.1111/j.1432-1033.1982.tb05886.x,

Publication Year  1982

PubMed ID  7037403,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.